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Left Ventricular Outflow Tract Obstruction (LVOTO)

Luke M. Wiggins, MD, S. Ram Kumar, MD, PhD, Winfield J. Wells, MD

Key Points

  • Classification is determined by level of obstruction.
    • Subvalvar
    • Valvar
    • Supravalvar
  • Pathophysiology: left ventricular pressure overload with resultant subendocardial ischemia and impaired left ventricular function.
  • Diagnosis and quantification by echocardiographic examination.
  • Surgical intervention is the mainstay of treatment. Though, timing and technique vary by classification of obstruction.

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Last updated: January 5, 2026