Pearson's General Thoracic
Adenocarcinoma of the Gastroesophageal Junction
Summary
Adenocarcinoma of the gastroesophageal junction includes tumors of the distal esophagus or gastric cardia that involve the gastroesophageal junction wherein the epicenter of the tumor is within 5 cm above or below the gastroesophageal junction. The major risk factors for this cancer include obesity and gastroesophageal reflux. Lymphatic metastases include abdominal nodes similar to gastric cancers and mediastinal lymph nodes similar to esophageal cancers. Most tumors are locally advanced at the time of detection and recommended treatment include preoperative chemotherapy or chemoradiation followed by surgery with radical lymphadenectomy.
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Last updated: June 14, 2024
Citation
Bolger, Jarlath C, et al. "Adenocarcinoma of the Gastroesophageal Junction." Pearson's General Thoracic Surgery. STS Cardiothoracic Surgery E-Book, Chicago: Society of Thoracic Surgeons, 2024. STS Surgery, consult.sts.org.
Bolger JC, Carroll P, Yeung JC, Gupta V, Darling GE. Adenocarcinoma of the Gastroesophageal Junction. In: Meyerson S, Mokadam N, Jacobs JP, eds. Pearson's General Thoracic Surgery. STS Cardiothoracic Surgery E-Book. Chicago: Society of Thoracic Surgeons; 2024. consult.sts.org. Accessed October 16, 2026.
Bolger, J. C., Carroll, P., Yeung, J. C., Gupta, V., & Darling, G. E. (2024). Adenocarcinoma of the Gastroesophageal Junction. In Meyerson, S., Mokadam, N., & Jacobs, J. (Eds.), Pearson's General Thoracic Surgery. STS Cardiothoracic Surgery E-Book. Chicago: Society of Thoracic Surgeons. consult.sts.org
Bolger JC, Carroll P, Yeung JC, Gupta V, Darling GE. Adenocarcinoma of the Gastroesophageal Junction [Internet]. In: Meyerson S, Mokadam N, Jacobs JP, eds. Pearson's General Thoracic Surgery. STS Cardiothoracic Surgery E-Book. Chicago: Society of Thoracic Surgeons; 2024. [cited 2026 October 16]. Available from: consult.sts.org.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC
T1 - Adenocarcinoma of the Gastroesophageal Junction
ID - 1418551
A1 - Bolger,Jarlath,
AU - Carroll,Paul,MB, BCh, MD, FRCS
AU - Yeung,Jonathan,MD, PhD, FRCSC
AU - Gupta,Vaibhav,MD
AU - Darling,Gail,MD, FRCSC
ED - Jacobs,J,
ED - Meyerson,Shari,
ED - Mokadam,Nahush,
Y1 - 2024/06/14/
BT - Pearson's General Thoracic
UR - https://consult.sts.org/sts/view/Pearsons-General-Thoracic/1418551/all/Adenocarcinoma_of_the_Gastroesophageal_Junction
PB - Chicago: Society of Thoracic Surgeons
DB - STS Surgery
DP - Unbound Medicine
ER -
