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Surgical and Endoscopic Therapy for the Columnar-Lined Esophagus

Cynthia Kassab , Robert M Van Haren, Wayne L. Hofstetter

Key Points

  • Endoscopic surveillance and management are dependent upon on the presence and degree of dysplasia
  • Ablative techniques such as radiofrequency ablation effectively eradicate dysplasia and metaplasia
  • Endoscopic resection can safely treat esophageal metaplasia, dysplasia and early carcinoma limited to the mucosa and superficial submucosa
  • Esophagectomy is no longer considered standard of care for high-grade dysplasia and most intramucosal carcinomas

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Last updated: June 16, 2025